NMOSD vs MS

NMOSD and MS are both chronic, autoimmune diseases that affect the central nervous system

MS, multiple sclerosis; NMOSD, neuromyelitis optica spectrum disorder.

Artwork of a patient with NMOSD, their loved one, and a person walking a dog; there are also multiple astrocytes

NMOSD and MS can have similar symptoms, but NMOSD is far less common

NMOSD is characterized by unpredictable attacks that can result in various disabilities, including blindness, paralysis, and, less frequently, death.

43

of patients with NMOSD

were initially misdiagnosed with MS*

73

of patients with NMOSD

tested positive for anti-AQP4, an antibody not present in MS

The wrong initial diagnosis of MS became less common after anti-AQP4 antibody testing was made commercially available in 2005 (20% of patients were misdiagnosed after 2005 vs 54.2% of patients before 2005).

In a study of 73 patients with NMOSD, 43% were initially misdiagnosed with MS.

73% of patients with NMOSD tested positive for AQP4 in a study out of 132 patients.

Anti-AQP4, anti-aquaporin-4.

Know the differences between the symptoms of NMOSD and MS

Select NMOSD symptoms or MS symptoms to view disease-specific symptoms.

 Vision changes
 Blindness
 Spasms
 Weakness
 Numbness
 Pain
Select
NMOSD or MS
 Fatigue
 Paralysis
 Hiccups
 Bowel dysfunction
 Nausea
 Vomiting